Enhancement of virus-induced leukemias and sarcomas in F 1 hybrid mice inoculated with parental spleen cells.
نویسندگان
چکیده
Asterisks preceding the title refer to studies in humans. 633 Cancer Permeation: Processes, Problems, and Prospects—A Review. Wilson I. B. Onuigbo. 637 The Effect of Adult Thymectomy and Adult Splenectomy on the Production of Leukemia and Stomach Neoplasms in Mice by N-[4-(5Nitro-2-furyl)-2-thiazolyl]acetamide. Samuel M. Cohen, Don B. Headley, and George T. Bryan. 641 Treatment of a Moloney Lymphoma with Cyclophosphamide and //-2-incompatible Spleen Cells. A, Fefer. 645 Suppression of Autochthonous Grafts of Spon taneous Mammary Tumor by Induced Allogeneic Graft Rejection Mechanism. Reiko Tokuzen and Waro Nakahara. 648 * HL-A Antigens in Solid Tumors.
منابع مشابه
The Fate of Parental Preleukemic Cells in Leukemia-suscep tible and Leukemia-resistant ¥1 Hybrid Mice*
(AKR X C3H)Fi mice were found to develop a high (89 per cent) incidence of spontaneous lymphoid leukemia. (AKR X C57BL)Fi hybrids had a low (8 per cent) spontaneous incidence of lymphoid leukemia but a significant (>16 per cent) incidence of reticulum-cell sarcomas. Pooled 6-month-oId preleukemic AKR spleen cells were injected intraperitoneally into 2to 5-day-old (AKR X C3H)Fiand (AKR X C57BL)F...
متن کاملThe Fate of Parental Preleukemic Cells in Leukemia-susceptible and Leukemia-resistant F1 Hybrid Mice.
(AKR X C3H)Fi mice were found to develop a high (89 per cent) incidence of spontaneous lymphoid leukemia. (AKR X C57BL)Fi hybrids had a low (8 per cent) spontaneous incidence of lymphoid leukemia but a significant (>16 per cent) incidence of reticulum-cell sarcomas. Pooled 6-month-oId preleukemic AKR spleen cells were injected intraperitoneally into 2to 5-day-old (AKR X C3H)Fiand (AKR X C57BL)F...
متن کاملIn vitro generation of cytotoxic lymphocytes against radiation- and radiation leukemia virus-induced tumors. III. Suppression of anti-tumor immunity in vitro by lymphocytes of mice undergoing radiation leukemia virus-induced leukemogenesis
Adult C57BL/6 mice exposed to fractionated irradiation or inoculated with the radiation leukemia virus (RadLV), develop high incidence (80-100%) of lymphatic leukemias within 3-6 mo. RadLV-induced lymphomas can elicit cytotoxic responses in vitro in lymphocytes of preimmunized syngeneic mice, a reaction that is dependent on the expression of membrane-associated viral antigenicity. As soon as 5 ...
متن کاملCell surface antigens of murine leukemias induced by radiation leukemia virus. Recognition of individually distinct cell surface antigens by cytotoxic T cells on leukemias expressing crossreactive transplantation antigens
The specificity of transplantation immunity and T cell cytotoxicity against leukemias induced by RadLV was examined. Subcutaneous inoculation of two RadLV leukemias induced in BALB/c mice, BALBRVB and BALBRVD, resulted in initial tumor growth in CB6F1 mice, followed by complete tumor regression. Mice that had rejected leukemias BALBRVB or BALBRVD were subsequently challenged with various tumors...
متن کاملImmunological Depression of Tumor Growth in F, Hybrid/Parental Strain Systems*
Evidence has been presented indicating that the intraperitoneal injection of lymphoid cells of one parental strain into F1 hybrid mice inhibits the growth of lymphoma cells of the opposite parental strain inoculated subcutaneously. The lymphoid cells were either preimmunized against the other parental strain and inoculated simultaneously with the tumor cells or inoculated, untreated, 5 days bef...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Cancer research
دوره 33 4 شماره
صفحات -
تاریخ انتشار 1973